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Safety Profile of TRT

28 November 2024 | 

Is Testosterone Replacement Therapy Safe?

Broadly speaking, yes, is safe. indicates that replacement therpay is considered safe in most men, and can also largely beneficial in improving health-related of life.

As a clinic with a strict patient-first approach, we will always make sure that the treatment we provide is what is right for you and your long-term health and we use

Why Understanding TRT is Essential to Your Health Journey

is a game changing option for men experiencing the effects of low (Low T), particularly those aged 40 upwards. With benefits ranging from energy to improved muscle tone and mood, TRT can make a big difference to the quality of your life. However, as with any medical treatment, understanding both it’s potential benefits and risks is essential for decision-making.

At Omniya Clinic London, we’re committed to guiding you through this journey with clear, research-based information. Let’s break down the potential risks, safety considerations, and side effects of TRT, so you can feel in your decision-making process.

What Are the Risks of Testosterone Replacement Therapy?

Although is generally considered safe when administered and monitored by qualified professionals, certain risks are associated with the treatment. These risks are often tied to individual health factors and require careful assessment and management. These risks can include cardiovascular concerns, considerations with prostae health, worsening of pre-existing sleep apnoea and considerations.

One of the most discussed concerns with TRT is it’s potential impact on heart health. Studies presented mixed findings in this area until early 2024 when the large multi-centre double blinded placebo-controlled randomised study known as TRAVERSE compelling evidence to say that patients on TRT are not at an risk of events compared to the general public(1). There is an excellent review article written subsequently by Professor Hackett titled "Long Term Cardiovascular Safety of Testosterone Therapy: A Review of the TRAVERSE Study", which summarises the findings of what is considered one of the largest and most robust studies on the risks and of TRT(2).

At Omniya Clinic, we usethorough pre-treatment assessments to determine each patient’s cardiovascular health, ensuring TRT is safe for those with or without pre-existing heart conditions.

The relationship between Testosterone Replacement Therapy (TRT) therapy and prostate health has been a subject of research for decades. Historically, some doctors avoided TRT due to concerns that it could accelerate prostate cancer growth. However, according to the Endocrine Society’s clinical guidelines(3), recent data does not support a direct link between and an increased risk of prostate cancer in otherwise healthy men. Nonetheless, the guidelines regular prostate monitoring for those undergoing TRT. In line with this recommendation, our team at Omniya follows a careful monitoring protocol to safeguard prostate health.

TRT can potentially worsen sleep apnea, a condition that disrupts breathing during sleep, particularly in men who are overweight. Longterm risks of untreated sleep apnoea include heart attacks and strokes. Research published in the Journal of Clinical highlights that testosterone may play a role in increasing airway resistance, which can exacerbate sleep apnoea symptoms(4). Importantly, one of the common presenting symptoms of a patient with low testosterone is losing weight and weight gain; this is also one of the commonest causes of sleep apnoea. TRT weight loss and muscle gain and therefore can be helpful in the reversal of obstructive sleep apnoea. At Omniya, our initial assessments include a thorough examination of any sleep disorders, helping us identify individuals at risk and adjust treatments as needed. It is important if we feel someone may have sleep apnoea that this is explored and investigated (and treated if required) first, before starting TRT.

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By supplementing testosterone, the body may reduce its own production of the hormone, which can lead to lower sperm production. This is an essential consideration for men planning to start or expand their families. To mitigate this risk, adjunctive treatments like human chorionic gonadotropin (HCG) can be used alongside TRT. Studies have found that HCG therapy could help maintain sperm production in men receiving testosterone therapy, however more is needed in this area, particularly around the longterm use of HCG to maintain fertility(5).

Safety Measures at Omniya Clinic

Patient safety is at the heart of our program at Omniya Clinic. Here’s how we ensure that every treatment is safe, effective, and personalised:

What are the Side Effects of Testosterone Replacement Therapy (TRT)?

Just as with any medical treatment, can have side effects. However, most side effects are mild and manageable. Here are some that you may encounter:

The good news is that many of these side effects are manageable with lifestyle adjustments or changes to your treatment plan. At Omniya Clinic, our team is on hand to provide guidance and support every step of the way.

Long-Term Considerations: What Does the Research Say?

The long-term impact of is a growing area of research. While early studies raised questions, more recent findings are the potential for long-term benefits, particularly in areas like bone health, cognitive function, and metabolic health.

Making an Informed Decision

Choosing is a highly personal decision that involves weighing the potential benefits and risks. At Omniya, we encourage all prospective patients to have open with our specialists, exploring their symptoms, goals, and any questions they may have. Here are some practical steps to consider when thinking about TRT:

We believe that knowledge is power. Our at Omniya Clinic is to provide every patient with the they need to make informed decisions about their health and well-being.

to discuss TRT options.

The Path to Renewed Vitality Starts Here

can be a life-changing treatment for men with low testosterone. By understanding its risks, safety considerations, and side effects, you can make an decision that aligns with your health goals. At Omniya Clinic London, our experienced team is committed to delivering safe, effective, and personalised care, helping you achieve optimal health and well-being.

If you’re experiencing symptoms of low and are considering TRT, take the first step towards renewed energy, confidence, and vitality with Omniya Clinic. Our team of experts is ready to guide you on your journey to better health.

to start your journey with TRT

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Dr Aman Chungh is a highly regarded men’s health physician and medical author whose work bridges the gap between clinical expertise and accessible health education. With over a decade of experience in general practice, he has refined an approach that seamlessly integrates insights from medicine, surgery and holistic health. His clinical journey has deepened his understanding of the complex interplay between hormones, mental well‐being and physical vitality - a perspective that enriches his written to the field.

A proud alumnus of the University of Southampton, Dr Chungh obtained his Bachelor of Medicine and Bachelor of Surgery degree in 2014, his success in both a Bachelor of Science and a Bachelor of Medical Sciences. This robust academic foundation, combined with years of hands‐on patient care, fuels his commitment to remaining at the forefront of medicine. As an author, he skilfully translates intricate medical principles into engaging, reader